| The most sad type of Cancer | Bates is the Bible | Nociception | Applied Neurology.. uh oh | Jack of All Trades | 
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					  Lung, Breast, Skin					 
					
					 What are common cancers to metastasize to the brain? (3) 
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					  1+					 
					
					 If someone is hyporeflexic, but still has a response what would their reflex grading scale be? 
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					  Parenchyma of the brain 
					Pia mater, arachnoid mater, parts of the duramater Ependymal and choroid plexus Skull except periosteum 
					 What is pain insensitive in the brain? 
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					  thalamus, hypothalamus, pineal gland, pituitary gland					 
					
					 What is the diencephalon 
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					  CT or PET Scan - whole body to ID cancer, biopsy					 
					
					 What is Diagnostics used for Brain tumours? 
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					  more males than females → except meningiomas, which occur more frequently in women					 
					
					 What sex is more likely to get a brain tumour? 
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					  a series of involuntary, rhythmic muscular contractions in response to a rapid muscle stretch reflex					 
					
					 What is clonus? 
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					  pain caused by abnormal neural activity that arises secondary to injury, disease, or dysfunction of the nervous system 
					Central pain - caused by CNS dysfunction, such as ischemic stroke, phantom limb pain Peripheral pain - caused by damage to peripheral nerves burning, deep pain 
					 What is neuropathic pain 
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					  Problems with vision					 
					
					 What is the presentation of a brain tumour in the Occipital Lobe 
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					  without treatment: 1 month  
					with treatment: < 1 year 
					 What is the prognosis of Brain Tumours? 
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					  Primary arise from the CNS and brain itself, secondary metastasize to the brain					 
					
					 What is the difference between primary and secondary brain tumours? 
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					  inability to passively flex neck due to increased tone in neck musculature					 
					
					 What is nuchal rigidity 
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					  pain that is triggered by chemical, mechanical or thermal stimuli (noxious stimuli) 
					Somatic pain (MSK) - localized and sharp pain Visceral pain - dull, diffuse and deep pain 
					 What is nociceptive pain 
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					  Problems with auditory, memory, or speech - aphasia					 
					
					 What is the presentation of a brain tumour in the Temporal Lobe 
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					  C1-C3 joints, ligaments, suboccipital muscles, Lev scap, trapezius, SCM					 
					
					 What is 2 structures that can give rise to headaches 
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					  Seizures, Focal Neuro deficits, Headaches, Cognitive deficits					 
					
					 What is the most common clinical features of a brain tumour? (4) 
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					  Accessory nerve, innervates SCM and Trapezius - test these muscles, Cervical rotation/flexion, shoulder elevation					 
					
					 What is Cranial nerve XI? What does it innervate? How would you test it? 
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					  False - only will cause pain if pressing on a pain sensitive structure or increasing cranial pressure					 
					
					 True or false: A brain tumour will always cause pain 
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					  Problems with reasoning, movement, planning, emotions, speech, problem solving resulting in personality changes, weakness, aphasia, apraxia					 
					
					 What is the presentation of a brain tumour in the Frontal Lobe 
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					  A- advance preparation 
					B- build a therapeutic environment/relationship C- communicate well D - deal with patient and family reactions E - encourage and validate emotions 
					 What is the ABCDE of breaking Bad News 
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					  30% are primary (of which, 40% are benign), 70% secondary in adults 
					In kids, most are primary 
					 What percentage are primary vs secondary brain tumours in adults? 
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					  Test pain (pin prick vs dull), temperature (hot vs cold) along dermatomes					 
					
					 How would you test the spinothalamic tracts? 
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					  nociceptors detect stimulus → conversion of stimulus to an electric signal → C fibers and Aδ fibers carry afferent input to the dorsal horn of SC → secondary nociceptive neurons in the spinothalamic tract carry afferent input to the thalamus → pain perception and a response sent along efferent pathways to modulate pain					 
					
					 What is the pain pathway 
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					  Problems with orientation, perception and recognition of sensory stimuli or faces, understanding					 
					
					 What is the presentation of a brain tumour in the Parietal Lobe 
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					  autonomic, endocrine changes 
					Medulla CTZ NTS gastric dysrhythmias 
					 What is the pathophysiology of Nauseau 
					(just name some big pathways involved)  |