This document identified 3 basic ethical principles to address ethical issues regarding the conduct of research

This principle stresses the idea that the burdens and benefits of research should be fair and just.

This assessment requires IRBs to consider the possible harms or benefits associated with subject participation in research. The goal is to maximize benefit whenever possible.

This 40- year experiment in Alabama prompted the creation of the National Commission for the Protection of Human Subjects.

This principle asserts that individuals should be treated as autonomous agents who are able to make their own decision regarding their involvement in research.

Researchers should be fair and just when selecting subjects to avoid unethically placing the burden of harm on disadvantaged or vulnerable populations.

Created as a result of war crimes committed during WWII, this code of ethics was the first international document which advocated voluntary participation and informed consent.

This principle asserts the idea that researchers must put forth effort to secure the well-being of participants.

This ensures individuals are able to voluntarily agree or disagree to take part in research. Information should be provided in a clear and accurate manner that describes all research procedures, costs, risks, etc.