The Anthrax Battle Jeopardy Template

Group 1	Group 2	Group 3	Group 4	Miscellaneous
100 CMG2 or TEM8. What two receptors can the anthrax toxin bind to on the cell surface?	100 Swelling from fluid moving into the lumen. What effect did the edema toxin have on the rat intestines?	100 Bacillus. Gram positive. What type of bacteria is anthrax? What would you expect from a gram stain?	100 Ninety five percent. What is the death rate of untreated inhalational anthrax?	200 2001. When was the anthrax bioterrorism attack in the United States?
200 Early 2000s. When was the anthrax toxin mechanism discovered?	200 Protective antigen, lethal factor, and edema factor. What are the three components of anthrax toxin?	200 IHC assay. What was the main method used in the paper?	200 Vaccine or no vaccine. What are the 2 pre-attack strategies?	400 Coal. Anthrax was named after a Greek word. What does this word translate into in English?
300 Src or Fyn What phosphorylates the receptors when toxin binds?	300 Bradycardia and hypotension. What results were seen from the telemetry part of the study?	300 Antibiotics can interfere with the presence of the anthrax bacteria in the blood. What is the main issue with current testing techniques?	300 Quality-adjusted life-year. What is a QALY?	600 Boxcars. What is anthrax said to resemble under the microscope?
400 L-capsule. In the focus article, what was essential for the pathogenicity of B. anthracis?	400 Loss of hematopoietic cells and loss of osteoblasts and osteocytes. What effect was seen in the bone marrow and bone?	400 The endospore that allows it to be stored in storage for long periods of time. What feature makes anthrax a prime choice for a bioweapon?	400 No vaccination, vaccination alone, antibiotic alone, vaccine and antibiotic. What are the 4 post-attack strategies?	800 Cutaneous, inhalational, gastrointestinal, and infection by injection. What are the four types of anthrax infection?
500 Macrophages. What cells use the process of phagocytosis to engulf the B. anthracis spores?	500 Lesions of the brain. Inflammation of the meninges. What damage is seen in primates and humans but not in mice?	500 Zoonosis. Anthrax can be found in cattle and other grazing herbivores. What word is used to describe a bacteria that can pass from animals to humans?	500 Vaccine and antibiotic, and it saved $355 (or $434 in 2017). What was the best strategy and how much per person did it save?	1000 Yes. Has anthrax ever been used in military tests?

The Anthrax Battle

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