Epilepsy | Optogenetics | Model Organisms | Treatment Groups |
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What is Status Epilepticus
A continuous seizure lasting for 30 minutes, or 2 or more seizures without full recovery of consciousness between them
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What is blue
Channelrhodopsin is activated by ___light
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What is a rat
This model organism was used in this study
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What is the sham control group
This group had electrodes implanted in the guide cannula, no virus was injected and no light was used
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What is absence epilepsy
Patients with this type of epilepsy are often misdiagnosed with A.D.D. or frequent day dreaming
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What is yellow/green
Halorhodopsin is activated by____light
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What is a zebrafish
This aquatic organism has been used as a model organism in previous epileptic studies
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What is the light control group
This group is designed to control for the possible effect of light. No virus was injected
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What is generalized epilepsy
This type of epilepsy is more likely to be inherited
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What is excite
Channelrhodopsin is used to ____ neuronal activity
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What is a fruit fly
This is the smallest model organism used in epileptic studies
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What is the NpHR control group
This group had electrodes implanted in the guide cannula, the viral construct injected, but no light was delivered via the optical fiber
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What is lithium-pilocarpine
This drug was used to induce status epilepticus in the rat model
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What is inhibit
Halorhodopsin is used to ____ neuronal activity
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What is electrical and transgenic/mutant
These two methods of seizure inductions were not used in this study
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What is the experimental group
This group had implanted electrodes, injected virus, and light illumination after seizure induction
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