YOU DOWN WITH PPE | AGED LIKE MILK | IT'S COMPOUNDING TIME | UNDER PRESSURE | MISCELLANEOUS |
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At least 30 seconds
For general hand hygiene, how long should hands/forearms to elbows be washed with soap and water?
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22 hours
Timmy notices that the standard BUD for his Category 1 CSP is ≤ 24hrs but one of the components of his CSP has an expiration date of 22 hours. What is the BUD for his CSP?
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July 1, 2022
The new hazardous drug technician has been fully trained on hazardous drug compounding on July 1, 2021. When is the latest that they must be reassessed for competency?
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Neutral/negative pressure
In what type of pressure should hazard drugs be unpacked after they have been received?
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First air, mechanical/chemical wipe with 70% IPA
After a heavy lunch, Eminem is sugar wasted and starts getting lazy with his compounding techniques. The pharmacist notices that the critical sites might be contaminated, what are some things Eminem forgot to do?
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No!
Kaleem scored his dream oncology PGY2 and is receiving a shipment of cyclophosphamide. He suspects there to have been a breakage during shipping. Kaleem doesn’t want to expose himself and he has been extra careful during COVID, so he grabs his trusty N95 to in addition to a surgical mask to place over the N95. Is Kaleem adequately protected?
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≤ 12 hours
For Category 1 CSP’s, what is the BUD at controlled room temperature (20-25C)?
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At least every 6 months
How often should dynamic airflow smoke pattern tests be performed in the PEC?
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≥ 15 ACPH
What is the minimum number of ACPH that must come from the HVAC through HEPA filters located in the ceiling?
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Inverted to prevent condensation
The new non-UCSF APPE student who is not named Kaleem and Drew, just got done getting scolded for placing the surface samples face up during incubation. What is the proper way and why?
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Gloves > Gowns > Shoe Covers
When compounding hazardous drugs, order the following by PPE by how frequently it needs to be changed: shoe covers, chemotherapy gloves, and disposable gowns?
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Expiration date
During his IPPE, Jeremy finds a bottle of Vioxx that must have rolled under some shelves well over a decade ago. The only date on the bottle is September 2005. Is this the expiration date or beyond-use date?
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Every 6 months
How often should surfaces used to stage, compound, and administer hazardous drugs be sampled for hazardous drug residue?
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5, 7, 7
For hazardous drug compounding, what are the minimum ISO classifications of the primary engineering control, secondary engineering control, and anteroom?
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Yes
It’s 5pm on a Friday and Vinny has to deliver azathioprine tablets up to the 12th floor but he is really itching to get his weekend started. Can he tube the azathioprine up?
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Must report to the designated person
Drew just got this amazing tattoo of a butterfly on his lower calf, what must he do before working in a compounding area?
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28 days
Mr. Potato Head just got done making his first multiple-dose CSP with a BUD of 30 days and they’re so excited, his boss Mr. French Fry decides to grill him like a BBQ, he asks “how long before we can’t use this medication anymore?”
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3 years
How long must documentation for nonsterile compounded products be readily retrievable after preparation?
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≥ 12 ACPH
Stock bottles of clofarabine have just been received and must be stored for later use. How many air exchanges per hour must occur in the room where clofarabine stock bottles are stored?
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MFR is a record of procedures while a CR documents compounding performed for CSP's.
The newest big deal donor comes in to check out the new IV room they paid for, they notice two sets of records and state “hey I don’t want this room to get cluttered, what’s the difference between the Master Formulation Records and Compounding Records?” What do you tell them?
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Sporicidal agent, EPA- registered disinfectant, or sterile 70% IPA + low-lint wipers
What did Michael Jackson forget in this scenario?
Michael Jackson just picked up a job at the IV Room and just got this sweet new bag of vancomycin that he’s excited to compound. He moonwalks across the line of demarcation into the clean side of the ante-room with the vancomycin, only to be tackled by David who says “Michael you forgot something!” |
90 days
Aileen is compounding clobetasol ointment under nonsterile conditions, but the preparation does not specify a beyond-use date. What is the maximum beyond-use date she can assign the ointment?
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No, but a longer BUD can be assigned if passed.
Does sterility testing assure that there is 100% absence of contamination?
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Yes and an attempt to identify the microorganism to the genus level must occur
Air Samples just came back from the PEC with a 2 CFU/m3, is this a concern? If so, what should happen next?
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FDA MedWatch
A 5 year old patient has received Maxitrol ear drops for a recent earache that was compounded in house. The patient shortly developed an Aspergillus niger infection and the ear drops were found to be contaminated. What agency should be notified of this adverse event?
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