Candidacy | Donor and Transplant Types | Management | Complications |
---|---|---|---|
12 years old
What is the age cut off for MELD/PELD scoring system?
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Age
What is the most important donor factor?
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PT/INR, PTT, Fibrinogen
What labs are obtained as an indicator of the liver's synthetic function?
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Sepsis or rejection
What is the most common reason for readmission within the first 3 months post-transplant?
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Biliary atresia
What is the most common indication for a pediatric liver transplant?
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Primary non-function or delayed graft rejection
What risk does infection in the donor pose to the recipient? (List one)
|
To check the patency of hepatic vessels
What is the function of doppler ultrasound post liver transplant?
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Aggressive treatment with immunomodulators and high dose steroids
How is acute rejection usually treated? (List one)
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Albumin
What lab value is especially taken into consideration for the PELD score that MELD does not?
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Left Lateral Segment
What segment of the liver is transplanted in a pediatric patient?
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Adequate graft perfusion
What is the overarching goal of maintaining a high cardiac output?
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Tachycardia, fever, malaise, RUQ and right flank tenderness or pain, hepatomegaly, and increased ascites
What are the clinical signs of acute rejection? (List 2)
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Status 1A
What transplant status would a fulminant liver failure qualify under?
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True
True or False: Split liver transplants yield comparable results to conventional, whole liver transplant techniques.
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Calcineurin inhibitor
What category of immunosuppressant is Tacrolimus?
|
Hepatic artery thrombosis, hepatic vein thrombosis, portal vein thrombosis
What is one of the the vascular complications seen in the early post-op phase?
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Extrahepatic malignancy, irreversible/severe neurologic injury, multi system organ failure, active uncontrolled sepsis, uncorrectable life-limiting defects in other critical organs (kidney, heart, lungs, immunodeficiency)
What is one of the contraindications for a liver transplant? (List one)
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Abdominal compartment syndrome
What syndrome do you risk by using a bigger graft in a whole liver transplant?
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Mycophenolate Mofetil (MMF)
Which immunosuppresant is considered teratogenic, therefore females of child bearing age that are on this drug should be on birth control?
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Decrease immunosuppression to promote clearance
What is the treatment for EBV infection after transplant?
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