The Basics The Hepatoropic A,B,C's The Other Bugs Clinical Things The Treatment!
100
What are viral infections?
These are the most common cause of hepatitis, but other etiologies include autoimmune, medications, toxins, alcohol.
100
What is Hepatitis A?
This type of hepatitis is due to a single-stranded, nonenveloped RNA of the Picornaviridae family and transmitted via the fecal oral route.
100
What is EBV?
This virus typically causes infectious mononucleosis, but can progress to acute hepatitis, which is usually self-limiting.
100
What is increasing AST/ALT?
These are common lab findings early in hepatic injury.
100
What is Hepatitis A?
Patients suffering from this infection may be contagious for 2 weeks before and 7 days after the onset of jaundice and require good washing after toileting.
200
What is acetaminophen?
This commonly used medication causes a direct toxin induced necrosis as the mechanism of injury.
200
What is Hepatitis E?
This virus is a single-stranded non enveloped virus of the Hepeviridae virus and usually is self-resolving although can lead to fulminant liver failure.
200
What is CMV?
This infection is typically associated with neurological abnormalities, and classic periventricular calcifications found on head imaging, however it is also a cause of hepatitis with over 60% of infants have jaundice and hepatosplenomegaly.
200
What is rapidly falling AST/ALT?
This is a poor prognostic indicator of liver injury.
200
What is Hepatitis B?
Screening mothers for this virus prior to delivery is an important key to preventing transmission to the newborn in this illness.
300
What is vertical transmission from infected mothers?
This is the most common mechanism for newborns to contract hepatitis.
300
What is Hepatitis B?
This virus is an enveloped DNA virus that is a member of the Hepadnaviridae family and has an infection rate among exposed infants with infected mothers who do not receive any form of prophylaxis.
300
What is Adenovirus?
This virus may typically cause viral upper respiratory tract symptoms in children, however in 2022 there was a world wide outbreak in which children were progressing to fulminant liver failure and some even required liver transplant!
300
What is hypoalbuminemia and increased PT/INR.
These lab values indicate that hepatic synthetic function is altered.
300
What is Hepatitis A?
Postexposure prophylaxis with Immune Globulin Intramuscular is more than 85% effective in preventing symptomatic infection in this illness when given within 2 weeks of exposure.
400
What is activation of the innate and adaptive immune systems?
This is the mechanism of injury for liver injury due to viral etiologies.
400
What is Hepatitis C?
This virus is a small, single-stranded, enveloped RNA virus that is a member of the Flaviviridae family and vertical transmission is the primary source of pediatric infection.
400
What is Dengue Virus?
This is the most rapidly spreading mosquito-borne viral disease in the world and an estimated 50 million infections occur annually, and can cause severe hepatitis in pediatric patients as it progresses.
400
What is Hepatitis B?
This infection causes extrahepatic manifestations due to circulating immune complexes such as arthralgias, arthritis, polyarteritis nodosa, thrombocytopenia, and glomerulonephritis.
400
What is interferon alfa or lamivudine (B) or ribavirin (C)?
Hepatitis B & C may cause chronic illness, however, treatment is available with these medications.
500
What is 3 months?
With recovery from infection, liver morphology can return to normal in...
500
What is Hepatitis D?
This virus is caused by a RNA virus, and requires hepatitis B virus (HBV) as a helper virus
500
What is Herpes Simplex Virus?
This infection has a wide variety of presentations including vesicular skin lesions or CNS infections, however, it can also lead to multi-organ failure, with severe hepatitis and liver failure.
500
What is Hepatitis A and Hepatitis B?
These are two hepatotropic vaccines recommended in childhood.
500
What are severe vomiting and dehydration, altered coagulation, or hepatic encephalopathy?
These are indications for hospitalization of children with acute hepatitis.






Pediatric Hepatitis

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