Most Common Malignancies | Tumor Markers | Chemotherapeutic Agents | Tumor Lysis Syndrome | Everything Else |
---|---|---|---|---|
What is lung cancer (also most common in males)
This is the most common cause of cancer-related deaths in females
|
What is AFP
A patient with a history of hepatitis C is found to have a suspicious liver lesion on imaging, this is the tumor marker most likely to be elevated
|
What is ototoxicity, nephrotoxicity, neurotoxicity
Cisplatin commonly causes these side effects (name three)
|
What is lymphoma and leukemia
These two malignancies predispose patients to the highest risk of developing tumor lysis syndrome
|
What is nasopharyngeal carcinoma and Burkitt lymphoma
You would be most concerned about the development of these two malignancies in a patient who has previously had an EBV infection
|
What is prostate cancer (breast most common in females)
This is the most common cancer in males
|
What is chromogranin A
You would want to serially surveil this tumor marker in a patient who underwent a small bowel resection where the pathology revealed a carcinoid malignancy
|
What is the heart
Doxorubicin is known for causing toxicity in this organ
|
What is hydroxyurea, thalidomide, paclitaxel, etoposide, zoledronic acid, fludarabine, bortezomib
These drugs have been known to have a higher association with the development of tumor lysis syndrome (name a few, there are a bunch)
|
What is MALT lymphoma (bonus points for suspected carcinogenic agent in H. pylori)
A patient would be at increased risk of this malignancy if he had a history of poorly treated H. pylori infection and abnormal gastric mucosa found on EGD
|
What is squamous cell carcinoma (adenocarcinoma most common in USA)
This is the most common type of esophageal cancer worldwide
|
What is CEA
This tumor marker is most likely to be elevated in a patient who presents with vague abdominal pain, weight loss, thickened right colon with regional lymphadenopathy and multiple liver lesions
|
What is granulocyte colony stimulating factor
This drug is commonly used for neutrophil recovery following chemotherapy
|
What is hyperkalemia, hyperphosphatemia, hypocalcemia, hypocalciuria
These metabolic derangements are commonly seen as a result of tumor lysis syndrome
|
What is the APC gene
Although there are many potential mutations in the colorectal cancer cascade, a mutation in this gene is thought to be the most common first step
|
What is basal cell carcinoma
With 80% of these lesions presenting on the head and neck, this is the most common skin malignancy
|
What is testicular cancer
Contrary to its usual use, beta-HCG can be used as a tumor marker for this malignancy
|
What is Sweet's syndrome
This syndrome is a known side effect of GCSF and is composed of abrupt onset of tender skin plaques, fever, arthralgias, headaches, ophthalmic manifestations, and rarely oral or genital lesions
|
What is general anesthesia, pregnancy, high fever, steroids, monoclonal antibodies, biological immunomodulators
These are non-oncologic causes of tumor lysis syndrome (name one or two)
|
What is a Sister Mary Joesph nodule (pancreatic most common)
This religious-themed physical exam finding is associated with certain GI malignancies
|
What is the back (legs for females)
Melanoma is most likely to present in this region of the body for males (different from females)
|
What is PSA
This tumor marker has the highest reported sensitivity of any studied tumor marker
|
What is bleomycin and busulfan
These two chemotherapeutic agents have been known to cause pulmonary fibrosis
|
What is uric acid, potassium, phosphorous, calcium
The four components the comprise the Cairo-Bishop criteria
|
What is lymphoma
This malignancy has the distinction of being one of the only solid organ malignancies that is usually exclusively treated with chemotherapy regardless of stage
|