Sink the Ship






Differentials Picture of the Day Side Effects Grab Bag What you don't know....
What is PSC Cataract:
*NF2
*steroid induced
*Fuchs heterochromic iridocyclitis
What is Phenothiazine induced cataract
What are side effects of amiodarone
1.) Corneal Verticillata
2.) Anterior subcapsular opacities
What is:
1.) 3-5 hours
2.) 4-6 hours
3.) 2 days
4.) 7-14 days
Duration of action of:
1.) phenylephrine
2.) tropicamide
3.) cyclopentolate
4.) atropine
Who is Sally Ong
This first year did their internship in Framingham, MA
What is Cornea Verticillata:
*Amiodarone
*Fabry Disease
*indomethacin
*Chloroquine/hydroxychloroquine
*phenothiazines

What are Metabolic Cataracts:
1.) Snowflake Cataract: Diabetes and Downs
2.) Oil Droplet Cataract: Galactosemia: Inheritance
3.) Christmas Treet Cataract: Myotonic Dystrophy and hypoparathyroidism: Inheritance?
4.) Sunflower: Wilsons Disease: Inheritance?
What are side effects of pilocarpine
1.) brow ache
2.) increased salivation
3.) retinal tear, induced myopia and accomodation
What is:
Dexamethasone (strongest)
Prednisolone
Loteprednol
FML
Hydrocortisone (weakest)
Relative strength of topical steroids
1.) hydrocortisone
2.) loteprednol
3.) Prednisolone
4.) dexamethasone
5.) FML
Who is Andrew Lee
This resident's uncle is a veterinary ophthalmologist
What is Lenticonus:
A. Anterior (marked convexity of the anterior lens): Rule out Alport's syndrome (hereditary nephritis, deafness)
*Inheritance?
B. Posterior (marked concavity of the posterior lens surface): Usually idiopathic; may be associated
What is the double ring sign, optic nerve hypoplasia
Associated with De Morsier Syndrome
Nystagmus
absent septum pellucidum
May have deficiency of hypothalamic and pituitary hormones
What is the workup?
Associated with what syndrome?
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What are side effects of prostaglandin analogs
1.) Increases melanosomes
2.) CME
3.) hypertrichiasis
1.) What is phacoantigenic glaucoma
KP? Treatment?
2.) What is phacolytic glaucoma.
KP? Treatment?
1.) Autoimmunity to lens antigens from disrupted lens capsule can lead to this
2.) Hypermature cataract with lens proteins leak across an intact lens capsule can lead to this
Who is Duncan Berry
This resident was born with a club foot
What is ectopia Lentis: Describe the syndromes.
1.) marfan Syndrome:
2.) homocystinuria
3.) Cystinosis
4.) Sulfit Oxidase Deficiency
5.) Hyperlysinemia
6.) Weil-Marchesani
7.) Ectopia Lentis et Pupillae
8.) Ehlers-Danlos
What is Fuchs Heterochromic iridocyclitis
Usually no treatment - doesn't respond to steroids.
*Underlying infectious etiology?
What is the treatment?
What is a side effect of pilocarpine, topiramate, hydrochlorothiazide, sulfa and chlorthalidone
Induced Myopia
What is microspherophakia:
Faulty development of the secondary lens fibers during embryogenesis.
*What is the syndrome?
*Why do we treat pupillary block with cycloplegics?
What is the underlying embryologic pathogenesis?
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Who is Michelle Kim
This resident loves karaoke
What is:
1.) Fuchs heterochromic iridocyclitis
2.) Herpetic uveitis
3.) Posner Schlussmann Syndrome
4.) Sarcoidosis uveitis
Uveitis with elevated IOP
what is aniridia:
WAGR syndrome: wilms tumor, aniridia, genitourinary abnormalities and mental retardation
Workup: abdominal imaging
*What percent develop glaucoma?
What is the workup?
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What is a side effect of topical corticosteroids -leading to increased IOP
Increased expression of extracellular matrix protein fibronectin, polymerized glycosaminoglycans, and elastin
What is Surge
Phenomenon that occurs in cataract surgery when vacuum has built up because of an occlusion which is suddenly broken, leading to fluid in the higher pressure anterior chamber rushing towards the phaco tip
Who is Sally Ong
This resident's father is one of 12 children
Lebers congenital amaurosis
Congenital stationary night blindness
Congenital achromatopsia
Optic Nerve Hypoplasia
Optic Neuritis
Dominant Optic Atrophy
Rare: amblyopia/strabismus
Cone dystrophy
Paradoxical Pupils

Jeopardy Review: Cataract and Lens

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