Stain. Gram Stain. | Our House | Geography | Are you my host? |
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What is S. aureus?
This gram positive coccus is catalase and coagulase positive and typically forms clusters on gram stain.
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What is C. difficile; Fidaxomicin (or vancomycin)
Antibiotic use can lead to watery diarrhea and leukocytosis caused by this organism, first line treatment for which is this antibiotic.
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What is Hantavirus?
Infection with this organism can lead to pneumonia and hemorrhagic fever. It is commonly associated with the Four Corners region of the United States.
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What is ascariasis?
One of the most common worm infections worldwide, the eggs of this creature are swallowed and hatch, yielding larvae which migrate through the bloodstream to the lungs, from whence they are coughed up and swallowed, growing to maturity in the small intestine.
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What is S. pyogenes?
This gram positive coccus is bacitracin sensitive, beta hemolytic, and has M protein as a virulence factor.
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What is Legionella?
Infection with this water-borne pathogen can cause symptoms including pneumonia, N/V/D, and even neurological changes.
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Histoplasmosis, Itraconazole (Amp B if severe)
The organism responsible for causing this disease can be found within macrophages. Infected individuals may exhibit ulcers of the mouth, splenomegaly, pancytopenia, and erythema nodosum. Spelunkers who frequent the Mississippi and Ohio River valleys are at increased risk. It is best treated with this.
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What is Plasmodium falciparum? Why?
Of the malaria-causing protists, this species causes the most severe disease.
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What is Klebsiella pneumoniae?
This gram negative, oxidase negative bacillus forms mucoid colonies and is normal gut flora but associated with pneumonia in patients with alcohol use and/or diabetes.
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What is S. epidermidis, vancomycin.
This gram positive, coagulase negative coccus may colonize indwelling medical devices such as prosthetic joints and heart valves. First line treatment consists of this antibiotic.
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What is bubonic plague, Yersinia pestis.
BP is a 12 yo girl who presents to the ED with a 2 days history of fever, headache, chills, shortness of breath, cough, and chest pain. Her father reports that the family recently returned from a trip to the American Southwest, where BP was spotted playing with prairie dogs. Physical exam is significant for, among other findings, high fever and buboes in the right axilla. CXR shows necrotic pneumonia. This nationally notifiable disease caused by this facultative intracellular GNB should remain high on your differential.
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What is tularemia, Francisella tularensis?
This disease commonly presents with fever, chills, and lymphadonopathy and may also be associated with eye pain and redness, photophobia, pharyngitis, abdominal pain, cough, shortness of breath, and hepatosplenomegaly. Reservoirs include deer flies and rabbits. This bacteria is the causative agent.
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What is acid-fast? Tx?
A 56 yo male who recently immigrated from India presents with 1 month of worsening cough associated with fever, chills, and hemoptysis. Chest X-ray reveals a cavitary lesion in the right upper lobe. No organisms consistent with this presentation are visualized on gram stain. This stain is best suited to visualizing the most likely causal organism.
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What is Pseudomonas aeruginosa? Tx?
SJ is a 37 yo male who is being mechanically vented in the ICU after sustaining severe neruotrauma in an MVC. On hospital day 7, he develops hypoxemia. His ET tube is suctioned to obtain sputum samples, and gram staining shows these gram negative baccili.
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What is doxycycline (or chloramphenicol)?
A 34 yo male presents with 2 days of worsening headache, fever, rash, and abdominal pain. He notes that he recently returned from hiking in the mountains of North Georgia. On physical exam, rash is noted on the wrists, palms, trunk, ankles, and soles. Initiation of this treatment is most appropriate.
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What is Q fever?
DK is a 42 yo sheep farmer who initially presented to your clinic with 4 days of worsening fever to 104 deg F, headache, cough, and shortness of breath. You recommend that he go to the emergency department, but he refuses. One year later, after experiencing recurring fatigue, night sweats, headaches, and joint pain, he undergoes an echocardiogram concerning for endocarditis, but blood cultures are negative. This suspected diagnosis is confirmed with tissue biopsy and the patient is started on an 18 month course of doxycycline.
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