Sadness, feelings of worthlessness, irritability, fatigue, crying spells, apathy, restlessness, lack of concentration, withdrawal, sleep problems, changes in appetite, thoughts of suicide, and physical aches and pains

10-20%

Gastrointestinal problems, neurological disorders, chronic conditions like arthritis cardiovascular disorder, Alzheimer’s disease, Parkinson’s disease, respiratory conditions, and loss of bladder control.

Lack of key neurotransmitter chemicals in the brain, family history of depression, and traumatic life events.

It can be debilitating and may reduce their health and quality of life.

Diuretics: used by patients who have glaucoma and high blood pressure, Corticosteroids: used by patients with rheumatoid arthritis, Antidepressants, Drugs Like Levodopa: used by patients with Parkinson’s disease, Anticholinergics: used by patients with chronic obstructive pulmonary disease, Adrenergic Drugs: used by patients who are having asthma attacks

Isolation, facing mortality, limited mobility, being retired, financial issues, prolonged substance abuse, death of friends and loved ones, being divorced or widowed, and chronic medical conditions.

Extreme stress or trauma, complicated or chronic grief, alcohol, caffeine or drugs, family history, other medical or mental disorders, neurodegenerative disorders.

Restless Leg Syndrome, Sleep Apnea, Insomnia, Periodic Limb Movement Disorder, REM Behavior Disorder, and Circadian Rhythm Sleep Disorders.