Mechanism of actiom Drug interactions Side effects PK/PD Miscellaneous
100
What is valacyclovir and acyclovir?
Which two agents provide prophylaxis against HSV/VZV but not CMV?
100
What is swish and swallow; wait 15 minutes to eat or drink
How would you counsel a patient to use nystatin?
100
What is leukopenia/neutropenia
What is the most anticipated change you would see on a CBC after initiation of valganciclovir?
100
What is ganciclovir
What is valganciclovir the oral prodrug of?
100
What is Bactrim
Which drug is the most effective for PCP prophylaxis?
200
What is aspergillus?
Posaconazole and voriconazole provide prophylaxis for which type of fungal infection that fluconazole does not?
200
What is CYP 3A4?
Which enzyme is fluconazole an inhibitor of?
200
What is bronchospasm
What side effect is associated with inhaled pentamidine?
200
What is take with a high fat meal
How would you counsel a patient to use atovaquone?
200
What is donor positive, recipient negative
Which CMV serologic status is considered high risk?
300
What is interferes with fungal cytochrome P450 activity decreasing ergosterol
What is the mechanism of action of fluconazole?
300
What is potassium and SCr?
What monitoring parameters should you keep an eye on when starting Bactrim in someone on an ACE inhibitor?
300
What is voriconazole?
What azole has the side effect of visual disturbances?
300
What is the tablets
Which Posaconazole formulation can be taken without regards to food?
300
G6PD
What enzyme should you test for before starting dapsone?
400
What is inhibits viral DNA synthesis (inhibits binding of deoxyguanosine triphosphate to DNA polymerase)
What is the mechanism of action of ganciclovir?
400
What is CYP 2C9?
Bactrim and warfarin interact through which enzyme?
400
What is hemolytic anemia, methemoglobinemia
Name an effect of dapsone on blood counts
400
What is every 4 weeks
Inhaled pentamidine is dosed at what interval?
400
What is What is false- dapsone has a sulfone group
True/false: we can assume patients with anaphylaxis to bactrim can safely take dapsone
500
What is competitive antagonist of para-aminobenzoic acid
What is the mechanism of action of dapsone?
500
What is voriconazole or posaconazole?
Which azole antifungals are strong inhibitors of CYP 3A4?
500
What is liver function tests (monitor for elevation of liver enzymes)
What lab value should you obtain before starting any azole therapy?
500
What intestinal mucosal cells and hepatocytes
How is valganciclovir converted to ganciclovir?
500
What is a full meal or acidic beverage?
What must a patient consume with posaconazole suspension (must name 2 options to receive credit)






Infection prophylaxis

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