Annoying Boxes | Cytotoxic Lymphocytes | Natural Killer Cells | Important Proteins | Vaccines |
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What is memory?
This function was, until recently,thought to be an exclusive function of B and T-cells only
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What are CTLs?
This cell recognizes target cells via class I MHC-antigen complexes
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What is the bone marrow?
This is the lymphoid organ where Natural Killer Cells are produced
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What is granzyme b?
This serine protease is secreted from cytotoxic T cell granules and induces apoptosis in the target cell
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What is live attenuated?
This type of vaccine is composed of pathogens that can grow and replicate in the host but cannot cause disease
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What is Africa or Asia?
These two continents have shown recent increases in polio infections (name one)
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What are perforins, granzymes, IFN-ɣ, TNF, Fas ligand (FASL)?
What effector molecules are produced by CTLs and NK cells? (name three)
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What is MHC class I?
The lack of this receptor is the main way that NK cells detect potentially harmful cells
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What are caspases?
These cysteine proteases are the master orchestrators of apoptosis
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What is passive immunity?
This type of immunity occurs naturally when a mother’s IgG antibodies are passed to the fetus through the placenta
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What is horse antivenin?
This agent is used to activate passive immunization against Black widow spider bites
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What is an NK T Cell?
A hybrid between a CTL and an NK cell, it primarily uses FASL to destroy target cells
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What is KIR?
Inhibitory receptors come from this diverse immunoglobulin-like family
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What are LFA-1 and ICAM1?
These two membrane-bound proteins interact to form a synapse between cytotoxic T cells and target cells so that granule proteins can’t diffuse away from the cells
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What is an inactivated or killed vaccine?
This type of vaccine often requires boosters to generate a strong enough immune response
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