Annoying Boxes Cytotoxic Lymphocytes Natural Killer Cells Important Proteins Vaccines
100
What is memory?
This function was, until recently,thought to be an exclusive function of B and T-cells only
100
What are CTLs?
This cell recognizes target cells via class I MHC-antigen complexes
100
What is the bone marrow?
This is the lymphoid organ where Natural Killer Cells are produced
100
What is granzyme b?
This serine protease is secreted from cytotoxic T cell granules and induces apoptosis in the target cell
100
What is live attenuated?
This type of vaccine is composed of pathogens that can grow and replicate in the host but cannot cause disease
200
What is Africa or Asia?
These two continents have shown recent increases in polio infections (name one)
200
What are perforins, granzymes, IFN-ɣ, TNF, Fas ligand (FASL)?
What effector molecules are produced by CTLs and NK cells? (name three)
200
What is MHC class I?
The lack of this receptor is the main way that NK cells detect potentially harmful cells
200
What are caspases?
These cysteine proteases are the master orchestrators of apoptosis
200
What is passive immunity?
This type of immunity occurs naturally when a mother’s IgG antibodies are passed to the fetus through the placenta
300
What is horse antivenin?
This agent is used to activate passive immunization against Black widow spider bites
300
What is an NK T Cell?
A hybrid between a CTL and an NK cell, it primarily uses FASL to destroy target cells
300
What is KIR?
Inhibitory receptors come from this diverse immunoglobulin-like family
300
What are LFA-1 and ICAM1?
These two membrane-bound proteins interact to form a synapse between cytotoxic T cells and target cells so that granule proteins can’t diffuse away from the cells
300
What is an inactivated or killed vaccine?
This type of vaccine often requires boosters to generate a strong enough immune response






Immunology Jeopardy

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