| What is gene therapy? | The Process of gene therapy | BONUS! |
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-an experimental technique that uses genes to treat or prevent certain diseases
What is gene therapy?
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Retroviruses and adenoviruses
What are the 2 types of viruses that are often used as vectors in gene therapy?
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-Many potential risks
(infection, mutations, toxicity, inflammation... ) -Difficult to insert genes directly into the cells -Gene therapy is an experimental technique -Expensive
Name one disadvantage to gene therapy.
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Answers may vary
What is an approach to gene therapy?
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Vectors contain DNA and are in charge of delivering the new gene to the mutated cell. Viruses are often used as vectors in gene therapy.
What does a vector do?
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-Enabling other viruses to act as vectors; some viruses scientists are currently working with include Herpes Simplex Virus (HSV) and Human Immunodeficiency Virus (HIV)
-It is believed that gene therapy may become one of the most effective cancer treatment method
What can be expected in the future of gene therapy?
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-Cystic fibrosis
-Heart disease -Cancer -AIDS
Name two diseases that can potentially be treated with gene therapy?
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Some examples include:
Retroviruses: Can cause cancer, so they have their cancer causing genes remove. RNA. Adenoviruses: DNA replicates quickly once inserted and the expression of the new gene is only shown for a short period of time
Name two differences between retroviruses and adenoviruses.
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Causes inflammation and can cause organ failure.
How do unwanted immune system reactions have a negative impact on the body?
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It can treat diseases which currently have no cure.
Why could gene therapy change medicine?
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Recombination
Explain the lysogenic cycle and state which stage the viral genome is combined with the host chromosome.
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Since Bob has a recessive disorder, inserting a gene which is dominant over the sickle cell gene will ensure that the sickle cell traits are no longer expressed, although Bob will still be a carrier.
Bob has sickle cell anemia which is a recessive condition. In order to cure this disease, does a new gene need to be inserted, or does a mutated gene need to be inactivated.
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