Cell Organization | Membrane | Epithelium | Genetic Disorders | Drugs, Drugs, Drugs! |
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What is Receptor- Mediated Endocytosis?
Selective uptake of large molecules via clathrin dependent pits that interact with cargo receptors via Adaptin.
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What is cardiolipin?
This glycerophospholipid is found only in the inner mitochondrial membrane
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What is simple cuboidal epithelium?
This type of epithelium is found in the kidney tubules, thyroid follicles, surface of ovary, hepatocytes and small ducts of exocrine glands. Major functions include absorption, secretion and barrier.
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What is neurofibromatosis?
this autosomal dominant disorder is caused by a mutation on the NF1 gene. It is a classic example of variable expressivity and high penetrance
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What is acyclovir?
This drug is a drug that treats herpes and varicella zoster and is a nucleoside analog of deoxyguanosine and is only activated in infected cells.
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What is a Late Endosome?
Receives proteins for degredation and receives newly synthesized lysosomal enzymes from the Golgi
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What is phosphotidylcholine?
This glycerophospholipid is found on the outer leaflet of the plasma membrane.
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What is Pseudostratified Epithelium?
This type of epithelium is one layer of cells that vary in shape and height. The cells appear stratified and all cells are attached to the basement membrane. Found in the trachea, and male reproductive tract.
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What is marfan syndrome?
This autosomal dominant disorder is caused by a mutation in the FBN1 gene and causes a defect in connective tissue. People will present with tall stature, heart defects and chest wall deformity.
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What is cytosine arabinoside (araC)?
This drug is a nucleotide analog of cytosine and contains a 3'-OH and 2'-OH group that causes steric hinderance during DNA replication that results in chain termination.
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What is Smooth Endoplasmic Reticulum?
This organelle is abundant in cells that can perform lipid metabolism, detoxification and sequester calcium.
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What is dipalmitoylphosphatidylcholine (DPPC)?
This glycerophospholipid is found in lung surfactant and decreases surface tension of alveolar fluid.
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What is Hemidesmosomes?
This junctional complex consists of integrins and is made up of intermediate filaments. When antibodies are directed against BP230 and Type 18 collagen it is characterized by blister formation at epithelium attachment to basement membrane.
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What is homocystinuria?
This autosomal recessive disorder resembles marfan syndrome and is caused by a high levels of circulating homocysteine.
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What is etoposide?
This drug inhibits topoisomerase II in eukaryotes and is used as an anti-cancer drug .
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What are Microtubules?
Non-branching, rigid, hollow tubes made up of alpha and beta tubulin. This structure also aids in cell shape, movement and polarity.
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What are cerebroside, sulfatide, globoside, and ganglioside?
These four glycolipids are found on the outer leaflet and help make up the glycocalyx.
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What is Submandibular Gland?
This type of mixed exocrine gland is characterized as having more serous than mucus cells
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What is X-linked SCID?
This X-linked recessive disorder is caused by a defect in the gamma-chain of interlukin receptors and because of this T-cells are not able to mature which results in a deficiency of normal B-cell funtion
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What is Actinomycin D (Dactinomycin)?
This drug prevents strand separation in DNA replication and RNA transcription in both prokaryotes and eukaryotes. It can be used as an anti-cancer drug .
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What is stereocilia?
A type of actin filament bundle that is anchored to the terminal web. Found in the epididymis, proximal ductus deferens and sensory hair cells of inner ear .
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What is Sphingomyelin (sphingophospholipid)?
This phospholipid id found in the outer leaflet if the plasma membrane and contains and sphingosine tail. It can be found in myelin sheath around neurons.
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What is periodic acid schiff (PAS) stain?
This stain is used to stain carbohydrate rich areas such as goblet cells
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What are MELAS, MERRF, and lebers hereditary optic neuropathy?
These three disorders are classified as mitochondrial disorders
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What is chloramphenicol?
This drug is used in prokaryotes to inhibit peptidyl transferase thus inhibiting translation. At high levels it may also inhibit mitochondrial translation.
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