Usual age of onset is young adult to middle age (30-50)

Group of people afflicted the most with ulcerative colitis.

Used to treat severe and fulminant disease; administered orally, parenterally, topically. Reduces inflammation.

Lack of improvement and continued deterioration, profuse bleeding, perforation, continued stricture formation, cancer

If irritation and yeast growth occur, this can be dusted lightly on the peristomal skin.

Frequent fatty stool or steatorrhea

Infiltrate seen in mucosa and submucosa, with clumps of neutrophils found in the lumens of the crypt

Used to alter the immune response in patients with severe disease who have not responded favorably to other therapies – in maintenance regimens to prevent relapses

Type of surgery recommended when the rectum is severely diseased

Most common complication of an ileostomy which results from leakage of effluent.

Abdominal pain with predefecation

The feeling that you need to pass stools, even though your bowels are already empty. It may involve straining, pain, & cramping

Treats mild-to-moderate inflammation; used to prevent or reduce recurrences in long-term maintenance regimens.Examples are sulfasalazine (Azulfidine), olsalazine (Dipentum), mesalamine (Asacol, Pentasa)

Type of surgery in which a continent ileal reservoir (i.e. Kock pouch) is created by diverting a portion of the distal ileum to the abdominal wall and creating a stoma

Complication which occurs more commonly in patients with an ileostomy then in members of the general population because of changes in the absorption of bile acids that occur post operatively

Noncontinuous segment inflammation

Inflammation of the anus & the lining of the rectum affecting only the last 6 inches of the rectum

First-line therapy for IBD; encapsulated to prevent significant absorption in the stomach or duodenum; when absorbed, almost entirely removed by first-pass metabolism of the liver.

Surgical procedure of choice where the rectum can be preserved in that it eliminates the need for a permanent ileostomy.

Clinical term for an acute toxic colitis with dilatation of the colon. The dilatation can be either total or segmental. Inflammatory process extends into the muscularis; inhibits ability to contract

Course of disease is prolonged & variable. Complications are bowel abscess, fistula formation, and intestinal obstruction

Ulcerative colitis that involves the entire colon (large intestine)

Tumor necrosis factor inhibitor shown to effectively reduce acute symptoms and provide maintenance therapy for both ulcerative colitis & Crohn's disease.

Inflammation of the ileoanal pouch due to altered microbial levels

Increased risk of osteoporotic fractures due to decreased bone mineral density contributed to by this.