Dm Topic Discussion Jeopardy Template

Brand/Generic	MOA	Goals	Medication Classes	Things to Consider
100 What is metformin? Glucophage	100 What are SGLT-2 inhibitors? Inhibiting this reduces reabsorption of filtered glucose from the tubular lumen. This decreases the reabsorption of filtered glucose, lowers renal glucose threshold, and increases urinary excretion of glucose	100 What is an A1c >6.5%? A1c diabetes diagnosis	100 What are sulfonylureas? Glipizide Glyburide Glimepiride	100 What are SGLT-2 inhibitors? Caution using this class in patients with chronic genitourinary infections
200 What is Glucotrol? Glipizide	200 What are sulfonylureas? Stimulates insulin secretion from beta-cells by binding to adenosine triphosphate-dependent potassium channel receptors, regardless of glucose concentrations	200 What is an A1c <7%? Goal A1c for many non-pregnant adults	200 What are DPP4 inhibitors? Sitagliptin Saxagliptin Linagliptin Aloogliptin	200 What are glyburide and glimepiride? These two sulfonylureas are listed on the 2019 Beer's Criteria
300 What is Jardiance? Empagliflozin	300 What are TZDs? Peroxisome proliferator-activated receptor gamma agonists; increases insulin sensitivity and decreases hepatic glucose production	300 What is FBG >126 mg/dL? FBG diabetes diagnosis	300 What are GLP-1 agonists? Exenatide Liraglutide Semaglutide Dulaglutide Albiglutide Lixisenatide	300 What are GLP-1 agonists? This class has a BBW for risk of thyroid C-cell tumors
400 What is dulaglutide? Trulicity	400 What is metformin? Primarily inhibits hepatic glucose production	400 What is an A1c 5.7% to 6.4%? A1c pre-diabetes diagnosis	400 What are SGLT2 inhibitors? Jardiance Invokana Farxiga	400 What are TZDs? This class of medications is contraindicated in NYHA Class III and IV heart failure
500 What is Actos? Pioglitazone	500 What are DPP-4 inhibitors? This class inhibits an enzyme from breaking down GLP-1	500 What is BG 80-130 mg/dL? FBG or pre-prandial BG goal per ADA guidelines	500 What are meglitinides? Repaglinide Nateglinide	500 Insulin This class provides the highest efficacy in BG lowering

DM Topic Discussion

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