| KDIGO 2012 | Epoetin Beta |
|---|---|
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For CKD patients with anemia not being treated with an ESA, measure Hb concentration when clinically indicated at least __________ in patients with CKD 5HD
at least monthly in patients with CKD 5HD
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While generally, all epoetins should be stored at 2-8 dec, Epoetin beta can be interrupted from its cooling chain at room temperature (25 deg C) up to a maximum of _____ days
maximum of 3 days
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Diagnose anemia in adults and children >15 years with CKD when the Hb concentration is <13 g/dl in males and __________ in females.
<12 g/dl in females.
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Needle gauge of Epoetin Beta PFS is ________
27 G 1/2
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In general, we suggest that ESAs not be used to maintain Hb concentration above ___________in adult patients with CKD
above 11.5 g/dl in adult patients with CKD
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The maximum dose for Epoetin Beta is ________________
720 IU/kg/BW
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In all adult patients, we recommend that ESAs not be used to intentionally increase the Hb concentration above __________
above 13 g/dl
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Initial dose of Epoetin Beta via SC route may be started at _______________
20 IU x 3 per kg/BW/week
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In patients with CKD and anemia (regardless of age and CKD stage), include the following tests in initial evaluation of the anemia
Complete blood count (CBC)
Absolute reticulocyte count Serum ferritin level Serum transferrin saturation (TSAT) Serum vitamin B12 and folate levels |
In the clinical study “Comparison of the Therapeutic Efficacy of Epoetin Beta and Epoetin Alfa in Maintenance Phase Hemodialysis Patients” by Alice Loughnan, the median weekly epoetin dose requirement with Epoetin Alfa is 9,000 IU and only ________ IU for
6,733 IU for Epoetin Beta
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