Cell Molec Final 1 Jeopardy Template

Exam I	Exam II	Exam III	New Stuff	Wild Card
100 What is True True/False: DNA replication is semi-conservative. (5.1.9)	100 What is Crispr/Cas9 Alexa wants to mutate a specific gene. What technique should she use? (11.36-41)	100 What is Starch granules Where/how do plants store glucose? (17.9)	100 What is Undifferentiated cells that can divide to repair tissue. What are stem cells? (23.7)	100 What is Tumor suppressor Is p53 an oncogene or tumor suppressor? (21.26)
200 What is Loosens or tightens DNA to make genes accessible or inaccessible to transcription Describe the function of chromatin remodeling complexes. (4.35)	200 What is PCSK9 inhibitor, statin Marina has high cholesterol (hopefully not!). What are two things we discussed that she can take to help lower her cholesterol. (12.2.12-13)	200 What is Frequency, location (neurotransmitter as well) All action potentials are made alike. The intensity of stimulus depends on _____. The nature of the stimulus depends on _____. (13.45-48)	200 What is Necrosis Cell swelling Nuclear disintegration Dissolution of cell membranes Inflammation Involves whole organs or large part of the organ Apoptosis Cell shrinkage Chromatin condensation Cytoplasmic blebbing, apoptotic bodies No inflammation Single or small groups of cells Explain the differences between apoptosis and necrosis. (22.1.4)	200 What is This mutation in ras, which helps cause cell proliferation and division, permanently activates it. Explain why the RasG12V is an oncogene (19.1.7) This mutation in ras, which helps cause cell proliferation and division, permanently activates it.
300 What is phosphorylation or GTP binding/hydrolysis Two most common form of protein regulation is… (3.3.14)	300 What is Conservation of gene order in chromosomes despite shuffling. Define synteny. (10.2.15)	300 What is Cytochrome c Which has a higher redox potential, ubiquinone or cytochrome c? (16.21)	300 What is False True/False: A gene duplication of N-myc would reduce the likelihood of cancer. (24.24)	300 What is During development, a randomly selected x chromosome gets inactivated (heterochromatin) in females. Males have one x chromosome and females have two. How come females don't have superpowers that give them double the ability as males in x-linked genes? (one could argue that they do have superpowers)(4.43)
400 What is Remember to draw your replication fork! Name 5 components of DNA replication and their function (5.2)	400 What is Ligand gating Voltage gating Stretch or pressure gating Phosphorylation gating Name some of the different types of gated ion channels. (13.28)	400 What is MAP kinase What pathway does ras activate? (19.1.9)	400 What is Flippases What maintains the composition of the plasma membrane? It makes sure the specific phospholipids are on the correct side of the plasma membrane. (22.2.8)	400 What is The energy gets stored in the carrier molecules in oxidative phosphorylation (NADH, FADH), if you just burn it, all the energy gets released as heat. Why is stepwise oxidative phosphorylation of glucose so much more efficient than burning the glucose all in one step? (15.1.3)
500 What is Kuru Eating brains of deceased people How is kuru (a transmissible prion disease) contracted? (3.2.3)	500 What is RNA Poly I - most rRNA genes RNA Poly II - protein-coding genes, miRNA genes, plus genes for some small RNAs (e.g., those in spliceosomes) RNA Poly III - tRNA genes, 5S RNA gene, genes for many other small RNAs Name the type of genes that each eukaryotic RNA polymerase transcribes. (7.29)	500 What is When cholesterol is high, it binds to SCAP in the ER membrane. Nothing happens. When it is low, a vesicle containing SCAP and SREBP breaks off from the ER membrane. It fuses to the golgi where proteases cleave a portion of SREBP, which then goes into the nucleus and acts as a transcription factor for genes that produce cholesterol biosynthesis enzymes How do SCAP and SREBP regulate cholesterol levels? (14.24)	500 What is IF Biochemically heterogeneous (many subunits exist) Great tensile strength, flexible Not polar No motor proteins More stable A&T Homogeneous (monomers) More rigid Polar [(+) and (-) ends] Motor proteins More dynamic Name some differences between intermediate filaments and actin & tubulin fibers. (20.11)	500 What is Cytochrome C gets released from the mitochondria. It binds to the adaptor proteins which form the apoptosome and recruit procaspase 9. How does the mitochondria regulate cell death? (22.1.13)

Cell Molec Final #1

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