Safety and Tolerability let's talk about SEX baby
100
What is nausea constipation and vomiting
PI 6 text above table 2
These three are the most commonly reported adverse reactions to Brintellix at greater than 5% and twice placebo
100
What is section 6 PI
Males
Females
Which gender had the highest rates of sexual dysfunction when on Brintellix when
voluntarily reported :
When Asked ASEX
200
What is 2 weeks PI 2.4
This is the amount of time needed from discontinuing a patient from an MAOI to Brintellix or the time it takes to reach steady state
200
What is
Sex drive,
Ease of arousal
Ability to achieve an erection (men) lubrication ( women)
Ease of researching orgasm
Satisfaction of orgasm
These are the 5 categories of questions asked in the ASEX scale
300
What is 8%
This percentage rate An adverse event was reported at both the 15 and 20 mg dose and the reason for discontinuation
300
What is 3 Brintellix 2 placebo
Boulanger pg 1415
The number of patients who reported sexual dysfunction in the Brintellix group versus the placebo group in the 24 to64 week of the long term study
400
What is 10%
Pi 6.1
This is the % of patients who continued to experience Nausea at the conclusion of the pooled 6 to 8 week studies at 10 and 20 mgs.
400
What is 0%
This percentage of patients reported sexual dysfunction in the Katona study; the same percentage compared to placebo but 6% less than the duloxteine group
500
What is 75 mgs in men
Pi 10.1 human experience
This was the maximum single dose and gender tested for Brintellix
500
What is
2 females 0 males Brintellix
3 females 11 males Venlafaxine
In the Alvarez study, how many total patients had reported sexual dysfunction in the Brintellix doses compared to the 225 dose of venlafaxine






Brintellix

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