Safety and Tolerability | let's talk about SEX baby |
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What is nausea constipation and vomiting
PI 6 text above table 2
These three are the most commonly reported adverse reactions to Brintellix at greater than 5% and twice placebo
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What is section 6 PI
Males Females
Which gender had the highest rates of sexual dysfunction when on Brintellix when
voluntarily reported : When Asked ASEX |
What is 2 weeks PI 2.4
This is the amount of time needed from discontinuing a patient from an MAOI to Brintellix or the time it takes to reach steady state
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What is
Sex drive, Ease of arousal Ability to achieve an erection (men) lubrication ( women) Ease of researching orgasm Satisfaction of orgasm
These are the 5 categories of questions asked in the ASEX scale
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What is 8%
This percentage rate An adverse event was reported at both the 15 and 20 mg dose and the reason for discontinuation
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What is 3 Brintellix 2 placebo
Boulanger pg 1415
The number of patients who reported sexual dysfunction in the Brintellix group versus the placebo group in the 24 to64 week of the long term study
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What is 10%
Pi 6.1
This is the % of patients who continued to experience Nausea at the conclusion of the pooled 6 to 8 week studies at 10 and 20 mgs.
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What is 0%
This percentage of patients reported sexual dysfunction in the Katona study; the same percentage compared to placebo but 6% less than the duloxteine group
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What is 75 mgs in men
Pi 10.1 human experience
This was the maximum single dose and gender tested for Brintellix
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What is
2 females 0 males Brintellix 3 females 11 males Venlafaxine
In the Alvarez study, how many total patients had reported sexual dysfunction in the Brintellix doses compared to the 225 dose of venlafaxine
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