bacteriostatic, against gram + and - by inhibiting folic acid synthesis. Broad spectrum.

Bacteriocidal, destroy cell walls by beta lactem ring, bind to penicillin binding proteins, then lyse cell

Third generation cephalosporin, most effective against gram negative bacteria, IV/IM only, easily passes meninges, and diffuses into CSF, used to treat CNS infections. Avoid alcohol 72 hours after to prevent disulfiram effect.

Macrolide, prevent protein systhesis, bacterostatic, at high levels, bacteriocidal. Used against mycobacterium avium intracellulare, and H. Pylori

inhibit protein synthesis, bacteriocstatic, broad spectrum

RBC's, can supress bone marrow, lead to hemolytic, aplastic anemia, agranulocytosis, or thrombocytopenia

Anaphylactic reaction, watch for urticaria, pruitis, angioedema. If pt has hx of swelling/hives from penicillin, should not take cephalosporins

good gram positive coverage, poor gram - coverage, FIRST generation cephalosporin, used for surgical prophylaxis, and suseptible staph infections

strep infections, URI and LRI (h. influenzae) spirochetal infections, syphillis, gonorrhea, chlamydia, lyme disease

pregnant/lactating, children under 8
used with diary products, antacids, or iron products, binds to Ca, Mg, and AI
discolors teeth

Photosensitivity, steven johnsons syndrome, toxic epidermal necrolysis

Gram + bacteria, strep, staph, entro,

diarrhea, cramps, puritis, edema, potiential cross sensitivity with penicillin

40% greater risk of rhabdomyletis when taken with statins (statin/azole)
GI with erythromyacin (hepatotoxicity)

teeth discoloration, fetal skeletal abnormalities, superinfection, diarrhea, pseudomembranous colitis, vaginal candidis, gastric upset, enterocolitis, maculopapular rash after sun exposure, decreased effectiveness of oral contraceptives

crystals in urine, synergystic effect with diabetic meds, prone to hypoglycemia

penicillin combined with drug that inhibits beta lactamase, prevents resistance

Carbapenem, BROADEST spectrum antibiotic, bacterocidal, inhibit cell wall construction, resistant to b lactamse. Used for peritonitis and bacterial meningitis, body cavity and connective tissue infection

Quinolones, bacteriocidal, inhibit dna synthesis,
effective against gram - and some +
Indications: complicated infections (UTI/Respiratory)
post anthrax exposure

SIADH, gram negative and gram positive protozoa, ricketts, chamydia, syphyllis, lyme disease

UTI's, community acquired MRSA, pnumonitis jirovecci, URI's and outpatient staph infections

NSAIDS, oral contraceptives, warfarin
- take on empty stomach
- keep pt. for 30 minuets after admin to assess for allergy

may induce seizure activity, decrease with correct dose, superinfections, anaphylaxis, and pseudomembraneous colitis

ruptured tendons, do not give under 18 or over 65, prolonged QT intervals, do not take with CA, iron or MG

nephrotoxicity